dnes som sa docital toto:

Now, who might those people be on the other side of the Framingham graph who have low cholesterol levels and zero incidence of heart disease? Perhaps some of them have a genetic defect in the PCSK9 gene, which codes for the enzyme that degrades the LDL receptor. These people have a genetic defect that increases LDL receptor activity instead of decreasing it. This is essentially the opposite of familial hypercholesterolemia.
http://blog.cholesterol-and-health.com/2011/03/genes-ldl-cholesterol-levels-and.html