antihistaminika :: Remember, remember, the velvet November


node:	antihistaminika
template:	4
parent:	Covid-19 / Novel Coronavirus (2019-nCoV)
owner:	jurov
viewed by:
created:	23.08.2024 - 21:30:44

cwbe coordinatez:
101
8333809
8837211
8703087
9172132

ABSOLUT
KYBERIA

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tl;dr: Antihistaminika mozu zlepsit priebeh covidu, ide o lieky proti alergii ako cetirizin (Zyrtec) a loratadin (Claritine) u nas volnopredajne a maju minimalne vedlajsie ucinky.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903129/

Zaujimave ze uz sa o tom par rokov vie ale nejako to v tom sialenstve zapadlo.

000001010833380908837211087030870917213209172180

pisali sme to tu. ale konkretne s postcovidom, ja som mal cca 3 tyzdne po covide strasnu nadchu, stacila jedna zakladna volnopredajna pirula proti alergii (nazov si uz nepamatam ale mali sme to doma kvoli clenovi rodiny co to zobe) a do hodiny som bol uplne fit.

reakcie v podobnom duchu tu napisalo zopar dalsich idecok

000001010833380908837211087030870917213209172153

tiez som to kukol len rychlo, ale ten clanok co linkujes je dost zle napisany, nema to moc citacie a tak.

asi najlepsi zhrniak co som stretol bolo toto:

While there were proof-of-concept studies to use H1R antagonists to improve COVID-19 treatment paradigms, all these studies were quite limited and lacked placebo control. The addition of antihistamines seems reasonable and may even have other beneficial effects like the ACE2 interaction of desloratadine. However, there seems to be a lack of placebo-controlled studies, and current research seems to be the result of small tests conducted during the pandemic.

https://link.springer.com/article/10.1007/s00210-023-02796-9

000001010833380908837211087030870917213209172149

Pises ze "mozu zlepsit priebeh covidu" a ja to tam nevidim.

Vidim tam "to be of shown several antihistamines to be of interest" a "with good prognosis" a "even though the clear mechanism is not well known". Teda ze niektore skusky vyzeraju nadejne ale nic konkretne.

Alebo to citujes z nejakej inej studie?
Prebehol som v skratke niektorez tych referencovanych (11,12,15,16) a nenarazil som na ziadne konkretne zavery ktore by boli pre beznych ludi prinosne. To ze testovali cetrizin na intubovanych pacientoch a tam to moze byt prinosne nie je sprava pre beznych ludi.

Mozno preto to zapadlo ze to nepreukazalo pozitivny efekt pri beznej liecbe?

(btw ja aktualne beriem cetrizin denne, takze budem to testovat :) ale ja mavam priebeh aj bez neho lahky)