A hovoria VSETKY zapadne denniky a ministerstvo zdravotnictva FR prave o brufene alebo o tej sprave z thelanced a ACE2 inhibitoroch? Ja mam pocit, ze sa tu domiesali dve veci. Lebo v tej povodnej analyze sa hovori iba o tom, ze lieky na hypertenziu a pod, ktore pracuju prave s modulaciou (zvysuju) ACE2 inhibitorov, mozu sposobovat zhorsenie infekcie.

"We suggest that patients withcardiac diseases, hypertension, ordiabetes, who are treated with ACE2-increasing drugs, are at higher riskfor severe COVID-19 infection and, therefore, should be monitored for ACE2-modulating medications, such as ACE inhibitors or ARBs."

Brufen tiez funguje na principe ACE inhibitorov (znizuje ich aktivitu). A niekto, kto to zdielal dalej si to tam uz nejako asi dospekuloval. Ak som sa docital spravne, tak brufen ako taky sa neodporuca ani s liekmi na hypertenziu a inymi, ktore su zalozene na modulacii (zvysovani) ACE inhib.

"First, ibuprofen is processed through the kidneys, so other drugs that act on the kidneys can react badly with ibuprofen—especially angiotensin-converting enzyme (ACE) inhibitors, which lower blood pressure in the body and the kidneys.

When blood pressure in the kidneys goes from high to normal, the kidneys are preserved and stay healthy. But when blood pressure in the kidneys goes from normal to low, it is a recipe for kidney damage, which can happen to a patient on an ACE inhibitor who gets dehydrated or develops low blood pressure from other causes.

If you add ibuprofen to the mix, things can get even worse. Therefore, acetaminophen is a better choice for patients taking an ACE inhibitor."